- Journal of Basic and Clinical Health Sciences
- Vol: 5 Issue: 1
- Organoid As a Novel Technology for Disease Modeling
Organoid As a Novel Technology for Disease Modeling
Authors : Tolga SEVER, Ilgin CEVIK, Gizem ÇALIBAŞI KOÇAL, Ender Berat ELLİDOKUZ, Yasemin BAŞBINAR
Pages : 94-101
Doi:10.30621/jbachs.868837
View : 7 | Download : 2
Publication Date : 2021-02-26
Article Type : Review
Abstract :The organoid technology is capable to create more real-like in vitro models in terms of structure and function of the origin of the tissue. Since the three-dimensional model is able to illustrate disease pathology, cell differentiation, and recapitulation of self-renewal, lead organoid technology as a promising disease model to fill the gap between conventional two-dimensional, and in vivo disease models. The review describes the recent development of organoid disease modeling approaches.Keywords : Organoid, Disease modeling, Stem cell