- İstanbul Journal of Pharmacy
- Vol: 29 Issue: 1
- SYNTHESIS AND CHARACTERIZATION OF NEW 2-(ARYLIDENEHYYDRAZONO)-4-METHYL-5-(ARYLAZO) THIAZOLINES
SYNTHESIS AND CHARACTERIZATION OF NEW 2-(ARYLIDENEHYYDRAZONO)-4-METHYL-5-(ARYLAZO) THIAZOLINES
Authors : G. Çapan, N. Ergenç E. Ilhan, B. Dolatabadi
Pages : 43-48
View : 13 | Download : 8
Publication Date : 2015-09-09
Article Type : Research
Abstract :Seven new thiazole derivatives have been synthesized from the reaction of α-oxo-α-methyl-N-(phenyl/substituted) ethanehydrazonoyl chlorides (A) (1, 2), obtained from the reaction of diazonium salts of aniline. 4-iodoaniline, 4-bromoaniline, 4-toluidine and benzocaine with chloroacetone, and thiosemicarbazones of 4- methylbenzaldehyde, 4-fluorobenzaldehyde, and furfural. The structure of the end products were determined using analytical and spectral methods. Fungicidal, insecticidal, and plant growth regulating activity tests are being carried out at Sittingbourne Research Centre, UK. Key words: α-hydrazonoyl halides, thiosemicarbazones, thiazoles, tautomerism.Keywords : α-hydrazonoyl halides, thiosemicarbazones, thiazoles, tautomerism.