- International Journal of Secondary Metabolite
- Vol: 7 Issue: 4
- Antibacterial activity and essential oil composition of Calendula arvensis L.
Antibacterial activity and essential oil composition of Calendula arvensis L.
Authors : Hüseyin Servi, Cansu Vatansever, Ahmet Doğan, Vanya Majeed
Pages : 229-236
Doi:10.21448/ijsm.676985
View : 8 | Download : 2
Publication Date : 2020-12-15
Article Type : Research
Abstract :Essential oil composition and antibacterial activity of Calendula arvensis L. were investigated. The essential oil of aerial part was obtained through hydro-distillation using a Clevenger type apparatus with 0.38 (v/w) yield. The essential oil components were determined by GC-MS analyses. Thirty-six components were identified in the essential oil that represented 91.8 % of the oil. The major components of the essential oil were δ-cadinene (14.8 %), epi-cubebol (10.7 %), α-cadinol (8.5 %), cubenol (7.7 %), cubebol (7.2 %), 1-epi-cubenol (5.4 %) and ledene (5.1 %). Antibacterial activity of essential oil was observed against Staphylococcus aureus ATCC 29213, Bacillus cereus ATCC 14579, Pseudomonas aeruginosa ATCC 27853 and Escherichia coli ATCC 25922 by using a broth microdilution. The essential oil showed weak inhibitory activity against E. coli and B. cereus at 8 mg/mL. The oil didn‘t show any antibacterial activity against S. aureus and P. aeruginosa. These results revealed that the oil was rich in oxygenated sesquiterpenes as well as had a weak antimicrobial activity.Keywords : Calendula arvensis, Essential oil, Antibacterial activity, GC-MS