- Archives of Current Medical Research
- Vol: 3 Issue: 1
- Prognostic factors after pneumonectomy in non-small cell lung cancer
Prognostic factors after pneumonectomy in non-small cell lung cancer
Authors : Cemal Aker, Celal Buğra Sezen, Mustafa Vedat Doğru, Ali Murat Akçil, Umut Kilimci, Semih Erduhan, Levent Cansever, Muzaffer Metin
Pages : 6-12
View : 15 | Download : 4
Publication Date : 2022-01-31
Article Type : Research
Abstract :Background: This study aims to evaluate the factors affecting survival and mortality in patients who underwent pneumonectomy for non-small cell lung cancer. Methods: The study included 241 pneumonectomy patients. Demographic data, mortality, histopathological characteristics, tumor stages, and 5-year survival rates were analyzed. Results: The study included nine women (3.7%) and 232 men (96.3%). The patients’ mean age was 58.4±8.0 (34–81) years. Fortyfive patients (18.7%) were 65 years of age or older, and 196 patients (81.3%) were less than 65 years of age. The 30-day postoperative mortality rate was 7.9% (n=19). The only factor affecting mortality was determined as age 65 and over (p = 0.012). The median survival time was 52 months, and the 5-year survival rate was 49.4%. In multivariate analysis, advanced age, pN2 status, not receiving neoadjuvant treatment, performing sampling lymph node dissection, and not receiving adjuvant treatment were poor prognostic factors. Conclusion: Age, pN2 status, neoadjuvant and adjuvant therapy, and lymph node dissection technique were determined as the most important prognostic factors affecting survival in patients who underwent pneumonectomy for non-small cell lung cancer. Age was the most important factor affecting mortality.Keywords : Prognosis, Pneumonectomy, Survival Rate, Carcinoma, Non-Small-Cell Lung