- Hittite Journal of Science and Engineering
- Vol: 7 Issue: 4
- Preparation, Characterization and Evaluation of Some New Amides as Antimicrobial Agents
Preparation, Characterization and Evaluation of Some New Amides as Antimicrobial Agents
Authors : Şükriye Çakmak, Aysel Veysioğlu
Pages : 345-351
Doi:10.17350/HJSE19030000204
View : 5 | Download : 2
Publication Date : 2020-12-31
Article Type : Research
Abstract :The some new amide derivatives 1(a-c) and, 2d were synthesized by the two-step N-acylation of 4-nitroaniline or heterocyclic amine derivatives with acyl chlorides. All of the products were determined using 13C NMR, 1H NMR, FT-IR spectroscopies and elemental analysis. Antimicrobial activities of the molecules were evaluated against various bacterial and fungal species. The results show that the some new compounds exhibit good antibacterial and antifungal activities.Keywords : Amides, Secondary Amides, N-Acylation, Antimicrobial Activity, Characterization