- Hacettepe Journal of Biology and Chemistry
- Vol: 51 Issue: 2
- Investigation of Electrochemical Properties of UA At Al2O3NP/CPE and Development of Voltammetric Met...
Investigation of Electrochemical Properties of UA At Al2O3NP/CPE and Development of Voltammetric Method for its Determination in Serum
Authors : Rüveyda Üver, Funda Öztürk
Pages : 191-200
Doi:10.15671/hjbc.1225829
View : 13 | Download : 6
Publication Date : 2023-04-01
Article Type : Research
Abstract :The electrochemical properties of uric acid (UA) were determined by cyclic voltammetry (CV) and square wave voltammetry (SWV) at a carbon paste electrode modified with aluminum oxide nanoparticles (Al2O3NP/CPE) in 0.05 M pH 5.0 phosphate buffer. The adsorption properties of the molecule on Al2O3NP/CPE were investigated and the number of electrons transferred in the electrode reaction was calculated. A new voltammetric method for the determination of UA in human serum was also proposed. The linear operating range and limit of detection (LOD) of the method were found to be 0.1µM-230 µM and 0.1µM, respectively. The developed method for UA in serum showed high reliability, reproducibility, accuracy and precision.Keywords : : Uric acid, voltammetric method, sensor, aluminum oxide nanoparticles, Uric acid, voltammetric method, sensor, aluminum oxide nanoparticles