- Hacettepe Journal of Biology and Chemistry
- Vol: 47 Issue: 3
- Conventional and Microwave Assisted Synthesis of New Triazole Derivatives and Evaluation of Their An...
Conventional and Microwave Assisted Synthesis of New Triazole Derivatives and Evaluation of Their Antimicrobial Activities
Authors : Zeynep Özdemir, Inci Selin Doğan, Mehmet Abdullah Alagöz, Hasan Erdinç Sellitepe, Didem Kart
Pages : 277-286
Doi:10.15671/hjbc.626966
View : 12 | Download : 6
Publication Date : 2019-10-23
Article Type : Research
Abstract :I n this study, four new oxime ether derivatives were synthesized and their antimicrobial activities were evaluated. At the same time, a comparison of the efficiency of the conventional method of synthesis with the microwave method was investigated. The structures of synthesized compounds were confirmed by their IR, 1H-NMR, and HRMS spectra. Antimicrobial activity of the compounds was tested against two Gr (+) bacteria (S. aureus, E. faecalis), two Gr (-) bacteria (P. aeruginosa, E. coli), and three yeast-like fungi (C. albicans, C. krusei, C. parapsilosis) by modified agar dilution method.Keywords : Triazole, oxime ether, microwave synthesis, antimicrobial activity