- Eurasian Journal of Critical Care
- Vol: 3 Issue: 1
- L-Carnitine treatment in a child with valproic acid intoxication
L-Carnitine treatment in a child with valproic acid intoxication
Authors : Mehmet Özgür ARSLANOĞLU, Ebru KAÇMAZ, Gürkan BOZAN, Ener Cagri DINLEYICI, Burak ÖZKAN, Sabiha SAHİN
Pages : 36-38
View : 16 | Download : 5
Publication Date : 2021-04-15
Article Type : Other
Abstract :With its growing application in neurological and psychiatric diseases, valproic acid overdose due to acute and chronic use has been causing emergency admission. Asymptomatic cases of hyperammonemia may be found in valproic acid poisoning ranging from central nervous system depression to coma. While supportive therapy is adequate, in most cases active charcoal, levocarnitine supplementation, and treatment with naloxane and hemodialysis, when needed, can also be used. In the case study reported in this paper, we aimed to focus at bringing awareness to the use of levocarnitine in asymptomatic patients with valproic acid poisoning accompanied by hyperammonemia.Keywords : hyperammonemia, intoxication, L-carinitine, valproik acid