- Cukurova Medical Journal
- Vol: 48 Issue: 1
- Comparison of the effects of TIVA and inhalation anesthetic techniques on olfactory functions and ol...
Comparison of the effects of TIVA and inhalation anesthetic techniques on olfactory functions and olfactory memory: a randomized prospective study
Authors : Üstün Sezer, Rahşan Dilek Okyay, Hilal Ayoğlu, Bengü Gülhan Köksal, Gamze Küçükosman, Özcan Pişkin, Nilay Nur Gençoğlu, Ferruh Ayoğlu, Fikret Çinar, Işıl Özkoçak Turan
Pages : 11-19
Doi:10.17826/cumj.1133058
View : 15 | Download : 6
Publication Date : 2023-03-31
Article Type : Research
Abstract :Purpose: This study aimed to investigate the effects of different general anesthesia procedures on postoperative olfactory functions and olfactory memory. Materials and Methods: This prospective study was conducted with 97 patients. Patients were divided into three groups based on anesthesia induction and maintenance technique: Group P (induction and maintenance with propofol), Group PS (induction with propofol, maintenance with sevoflurane), and Group S (induction with sevoflurane, maintenance with sevoflurane). Butanol threshold and olfactory identification tests were administered 30 minutes (min) before the operation (T1) and 30 min (T2), 8 hours (h) (T3) and 24 h (T4) after the operation. Results: Butanol threshold values were increased at the T2 time point compared to baseline in all groups, which returned to baseline values at T3 only in Group P. There was a significant difference between Group P and Group S in terms of butanol threshold values at all time points except T1. When olfactory identification increased at T3 and T4 compared to baseline in Group P, there was a significant difference between T2, T3, and T4 time points in Group S, and between T2 and T3 time points in Group PS as compared to Group P. Conclusion: Propofol only causes a temporary impairment in olfactory functions in the early period and does not alter olfactory memory.Keywords : Koku işlevi, Propofol, Sevofluran, Koku hafızası