- Ankara Üniversitesi Eczacılık Fakültesi Dergisi
- Vol: 47 Issue: 2
- PHYTOCHEMICAL PROFILING AND HEAVY METALS COMPOSITION OF AQUEOUS AND ETHANOL EXTRACTS OF ANOGEISSUS L...
PHYTOCHEMICAL PROFILING AND HEAVY METALS COMPOSITION OF AQUEOUS AND ETHANOL EXTRACTS OF ANOGEISSUS LEIOCARPUS
Authors : Muhammad Mubarak Dahiru, Enoch Buba Badgal, Neksumi Musa
Pages : 311-323
Doi:10.33483/jfpau.1205941
View : 10 | Download : 3
Publication Date : 2023-05-20
Article Type : Research
Abstract :Objective: The present study aimed to investigate the phytochemical and heavy metals components of A. leiocarpus considering its applications in ethnomedicine. Material and Method: The phytochemical components were determined qualitatively and quantitatively gravimetrically, while component identification was done using (Gas spectrometer-mass spectrometer (GC-MS) technique. Heavy metals were quantified by atomic absorption spectrophotometer. Result and Discussion: Saponins and flavonoids were detected in the aqueous extracts in concentrations of 10.22% ±0.48, and 38.67% ±0.17 respectively, and concentrations of 17.37% ±0.65 and 19.63% ±0.60 respectively in the ethanol extract. GC-MS analysis identified 16 and 26 compounds in the aqueous and ethanol extracts respectively. In the aqueous extract, 5-Hydroxymethylfurfural, 1,2,4-Benzenetriol, and cis-Vaccenic acid had the highest peak areas of 46.24, 17.12, and 15.13% respectively, while in the ethanol extract 5-Hydroxymethylfurfural (14.40%), 1,2,3-Benzenetriol (12.29%) and -methoxybenzene-1,4-diol (7.54%) were the highest. Chromium (0.548 ppm ±0.030) was detected only in the aqueous concentration, while Cadmium had a concentration of 0.002 ±0.001 and 0.006 ppm ±0.002 in the aqueous and ethanol extract respectively. Lead was present with aqueous and ethanol extracts concentrations of 0.096 ±0.020 and 0.096 ppm ±0.040 respectively. Conclusively, the present study agrees with the claims for the traditional application of the plant in folkloric medicine to manage different ailments.Keywords : Ağır metaller, Anogeissus leiocarpus, GC-MS, fitokimyasal, profil oluşturma