- Yeni Üroloji Dergisi
- Vol: 18 Issue: 2
- The effect of an herbal agent "Tutukon®" on the spontaneous passage rates of ureteric ston...
The effect of an herbal agent "Tutukon®" on the spontaneous passage rates of ureteric stones
Authors : Rasim Güzel, Laurian Dragos, Ümit Yildirim, Bilal Eryildirim, Kemal Sarica
Pages : 108-114
Doi:10.33719/yud.2023;18-2-1187893
View : 46 | Download : 44
Publication Date : 2023-06-27
Article Type : Research Article
Abstract :Objective:: The objective of this study is to assess the efficacy of an herbal agent (Tutukon®) on the spontaneous passage rates of ureteral calculi 5-10 mm. Materials and Methods: 96 patients having a single radio-opaque ureteral stone 5-10 mm were randomized into two groups. Group 1 (n = 51) received Tutukon®, 45 mg/day (three times) in addition to conservative approach and Group 2 patients (n = 45) were followed with classical conservative approach during 4 weeks follow-up. The stone passage rates, stone expulsion time, change in weekly colic episodes and hospital readmission rates for colicky pain were compared. Results: Stone expulsion rates showed statistically significant difference between the two group (66.7 % vs 46.7 %, p = 0.048). Additionally mean time period required for the spontaneous passage of the calculi was meaningfully short in those cases receiving Tutukon® when compared with Group 2 patients undergoing conservative measures only (5.79 ± 2.39 vs 8.82 ± 3.48 days, respectively) (p = 0.001). Similarly, the mean renal colic episodes during follow-up period were significantly diminished in Group 1 patients (66.6 vs 36%, p = 0.001, respectively). Lastly, colic pain attacks were noted to be less in Group 1 and another advantage of"Tutukon®” was the relocation of the stones to a more distal part of ureter (35.2 vs 4 %). Conclusion: Use of Tutukon® in the medical management of ureteral calculi can accelarate the spontaneous passage rates and also relocate them into the lower portion of the ureter.Keywords : bitkisel ajanlar, medikal terapi, spontan pasaj, üreter taşları