- Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi
- Vol: 53 Issue: 2
- A recovered patient after myocardial injury related to Covid-19; a case report
A recovered patient after myocardial injury related to Covid-19; a case report
Authors : Recep Alanli, Murat Bülent Küçükay, Serkan Yalçin, Şahin Mursel, Bülent Ahmet Beşirbellioğlu
Pages : 125-127
Doi:10.20492/aeahtd.744574
View : 24 | Download : 3
Publication Date : 2020-08-31
Article Type : Other
Abstract :ACE2 receptors are reported to have an important role in myocardial injury in Covid-19. Direct myocardial toxic effect of virus, myocarditis, cytokine injury, microangiopathic injury related to virus infection may cause myocardial injury and eventually troponin levels increase. Those mechanisms are; unstable plaques in coronary arteries resulting in myocardial hypoxia, upregulation of ACE2 receptors in coronary arteries and cardiac tissue, direct toxic effect of virus towards myocytes, systemic inflammation, myocardial interstitial fibrosis, excessive immune response to interferon, increased cytokine release from helper T lymphocytes which lead to myocardial injury. In this reported case, clinical course was mild and outcome was good, patient was followed in ward and he did not need intensive care.Keywords : covid 19, myocardial injury, troponin