Vertebral Osteomyelitis: What has Changed in Last 10 Years?
Authors : Umran Şumeyse Elbahr, Yusuf Özdemir, Rıdvan Karaali, Ilker Balkan, Neşe Saltoğlu, Fehmi Tabak, Birgül Mete
Pages : 87-93
Doi:10.38175/phnx.1239682
View : 109 | Download : 303
Publication Date : 2023-07-01
Article Type : Research
Abstract :Objective: This study was conducted to describe the demographic, clinical, and microbiological characteristics of vertebral osteomyelitis in the last decade, mainly by comparing literature and the previous case series performed in our center. Material and Methods: This is a retrospective, observational, descriptive study performed between 2009-2019 at Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine. All patients were divided into three main groups: pyogenic, tuberculous and brucellar. Results: A total of 100 cases were included in this study. Of these 100 patients, 59 had pyogenic, 15 had brucellar and 26 had tuberculous spondylodiscitis. The disease developed postoperatively in 22 (37.4%) of the 59 pyogenic vertebral osteomyelitis cases. The common isolated microorganism was Staphylococcus aureus (n = 11), followed by coagulase negative staphylococci (n = 6). Brucellar vertebral osteomyelitis rate was lower than previous case series (15 vs. 24). The median time to improvement in the laboratory findings after the administration of the appropriate treatment was 14 days. PET-CT was diagnostic in 81.8% of pyogenic vertebral osteomyelitis patients, similar to MRI. However, PET-CT diagnosis rate was significantly low in tuberculous spondylodiscitis (3 out of 9, p = 0.040). Conclusion: S. aureus remained the most common etiologic agent. Coagulase negative staphylococci infection rate, mainly related to spinal surgery, and postoperative spondylodiscitis rate is higher than before. Brucellar vertebral osteomyelitis rate is lower, which is mostly related to effective animal vaccination and pasteurization. Although, MRI is the gold standard, PET-CT is a promising technique in diagnosis for pyogenic vertebral osteomyelitis.Keywords : Spondilodiskit, Vertebral Osteomiyelit, Piyojenik, Bruselloz, Tüberküloz