- Anatolian Current Medical Journal
- Vol: 4 Issue: 3
- Mean platelet volume (MPV) levels in subclinical hypothyroidism and its relation to serum lipid leve...
Mean platelet volume (MPV) levels in subclinical hypothyroidism and its relation to serum lipid levels
Authors : Zafer Ercan, Mehmet Emin Demir
Pages : 234-237
Doi:10.38053/acmj.1077780
View : 17 | Download : 3
Publication Date : 2022-07-26
Article Type : Research
Abstract :Background: Subclinical hypothyroidism (SCH) is a term to define a mild and early thyroid deficiency. Some reports claim SCH has an association with increased cardiovascular disease (CVD), especially in individuals 4 mIU/L TSH levels were labelled for SCH group. Both groups were evaluated for MPV, lipid profiles and epidemiological features. Results: SCH group had higher levels of MPV, total cholesterol (TC) and LDL cholesterol (LDL-C) levels (P<0.05, for each parameter). MPV had a positive correlation to TC and LDL-C (r=0,175 ve p=0,025; r=0,154 and p=0,043). However, a multivariate analysis that rendered the impact of age and gender revealed that SCH had no impact on MPV after adjustment for those parameters gender revealed that SCH had no impact on MPV after adjustment for those parameters (B=0,304; 95% CI: -0,021 – 0,628; p=0,066). Conclusion: SCH patients may have higher levels of MPV. However, age and gender had an impact on MPV levels and we think increased CVD risk in SCH patients is associated with factors other than MPV levels.Keywords : MPV, lipids, subclinical hypothyroidism