- Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi
- Vol: 21 Issue: 3
- Effect of New Water-Soluble Dendritic Phthalocyanines on Human Colorectal and Liver Cancer Cell Line...
Effect of New Water-Soluble Dendritic Phthalocyanines on Human Colorectal and Liver Cancer Cell Lines
Authors : Ebru Yabaş, Mustafa Sülü, Aykut Özgür, Yusuf Tutar
Pages : 689-695
Doi:10.19113/sdufbed.89035
View : 11 | Download : 4
Publication Date : 2017-08-08
Article Type : Other
Abstract :Human hepatocellular carcinoma (HepG2) cells and colorectal adenocarcinoma (DLD-1) cells were treated with the synthesized water soluble phthalocyanine derivatives to understand the effect of the compounds both on colorectal and liver cancer cells. The compounds inhibited cell proliferation and displayed cytotoxic effect on these cancer cell lines however; the effect of the compounds on healthy control fibroblast cell line was comparatively lower. The compounds can be employed for cancer treatment as anticancer agents.Keywords : Dendrimer, Anticancer activity, Liver cancer, Colorectal cancer