- Sakarya Tıp Dergisi
- Vol: 13 Issue: 2
- 10-Year Cardiovascular Risk, Serum Lipid Indices and High Sensitivity CRP in a Healthy Population
10-Year Cardiovascular Risk, Serum Lipid Indices and High Sensitivity CRP in a Healthy Population
Authors : Sinan Akinci, Ertan Akbay
Pages : 225-231
Doi:10.31832/smj.1166369
View : 13 | Download : 15
Publication Date : 2023-06-30
Article Type : Research Article
Abstract :Objective: It is very important to identify individuals at high risk of atherosclerotic cardiovascular diseases (ASCVD) and for this purpose, many risk calculation tools and parameters are used. In this study, we aimed to investigate the correlation between the ACC/AHA cardiovascular risk and serum lipid indices and high sensitivity C-reactive protein (hs-CRP) in a healthy population. Methods: Our study was conducted retrospectively on individuals aged between 40 and 79 years and with sufficient data, using the hospital database. Patients with a history of any chronic disease and active infection were excluded. Individuals were analyzed by grouping them into low ( 5%) estimated 10-year risk of ASCVD. Results: 184 individuals with a median age of 46 and 37.5% women were included in the study. The median 10-year estimated risk of ASCVD in the study population was 3% (1.3/5.98). The low-risk group had a significantly lower atherogenic index of plasma (AIP), Castelli I risk index (CR-I), and Castelli II risk index (CR-II) compared to the borderline to high-risk group (p <0.001 for all). However, CRP was not different between groups (p: 0.683). The 10-year risk of ASCVD was statistically significantly correlated with AIP (R:0.380; p<0.001), CR-I (R:0.467; p<0.001), and CR-II (R:0.482; p<0.001), but no correlation was detected with hs-CRP (R:0.065; p:0.381). Conclusion: The lack of correlation between ACC/AHA\'s risk calculation tool and hs-CRPsuggests that hs-CRP cannot be used as a high-risk indicator in these individuals or that this tool is insufficient to detect some high-risk patients.Keywords : C-Reaktif Protein, Kardiyovasküler Risk Skoru, Dislipidemiler