- Sakarya Tıp Dergisi
- Vol: 13 Issue: 1
- Leukoglycemic Index may be a Unique Parameter to Predict Mortality in Patients with Acute Myocardial...
Leukoglycemic Index may be a Unique Parameter to Predict Mortality in Patients with Acute Myocardial Infarction: Single Operator Experience
Authors : Fatih Kahraman, Halil ?brahim Durmu?, O?uz Kiliç
Pages : 118-123
Doi:10.31832/smj.1222605
View : 8 | Download : 4
Publication Date : 2023-03-16
Article Type : Research
Abstract :Background and Aim: Predicting high-risk patients is crucial in acute myocardial infarction (AMI). We aimed to investigate whether the leukoglycemic index (LGI) has a unique ability and to compare it with other inflammatory parameters in predicting in-hospital mortality in AMI. Methods: In this single-center study, we retrospectively analyzed all AMI patients hospitalized and followed by a single operator. Patients were divided into two according to in-hospital outcomes. Other inflammatory parameters (systemic immune-inflammatory index, platelet-lymphocyte ratio, neutrophil-lymphocyte ratio, triglyceride-HDL ratio, and LDL-HDL ratio), C-reactive protein (CRP), and LGI were calculated according to previously described criteria. Univariable and multivariable logistic regression analyses were used to find independent predictors. The receiver operating characteristic (ROC) curve was used to find the cut-off point of LGI and other parameters in predicting mortality. Results: A total of 304 patients with AMI were included in the study. The mean age was 62.18±11.89 and 74 (24.3%) of patients were female. The total death rate was 19 (6.3%). In univariate variable analysis, LGI was found as a significant predictor of mortality (p<0.001). After adjusting risk factors (age, coronary artery disease history, ejection fraction, CHA2DS2VASc score, creatinine, and CRP) in multivariable analysis, LGI was still found as a significant predictor of short-term mortality. ROC curve analysis showed that the area under the curve was 0.837 (0.704-0.971) with a sensitivity of 76.5% and with a specificity of 91.5% with a 3.39 cut-off value. Conclusion: Our study showed that LGI might be a unique parameter in predicting short-term mortality in AMI.Keywords : lökoglisemik indeks, akut miyokard enfaktüsü, mortalite, leukoglycemic index, acute myocardial infarction, mortality