- Osmangazi Tıp Dergisi
- Vol: 35 Issue: 3 - OSMANGAZİ TIP DERGİSİ / Osmangazi Journal of Medicine
- Hyperbaric Oxygen Experience on Treatment of the Bisphosphonate-Related Osteonecrosis of Jaw (Bronj)...
Hyperbaric Oxygen Experience on Treatment of the Bisphosphonate-Related Osteonecrosis of Jaw (Bronj): Case Report of a Metastatic Breast Cancer Patient
Authors : Evrim Bayman, Nilufer Bicakci, Evin Gulen
Pages : 0-0
Doi:10.20515/otd.31883
View : 18 | Download : 2
Publication Date : 2015-06-18
Article Type : Other
Abstract :SUMMARY: The Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is an exposed necrotic alveolar bone associated with intravenous (IV) administration of Bisphosphonate (BP) therapy of multiple myeloma and bone metastases without previous radiation therapy (RT) to the maxillo-facial region (1,2,3). Hyperbaric Oxygen (HBO) treatment is one of the option which used on treatment of BRONJ, via increasing stem cell mobilisation, decreasing oedema, inflammation, and accelerating to wound healing (4,5). In this report, the case with metastatic breast cancer who has BRONJ was presented, and treatment of BRONJ with HBO was discussed. ÖZET: Bifosfonata bağlı çene osteonekrozisi (BBCO) kemik metastazı veya multipl myeloma’da kullanılan intravenöz bifosfonat ile ilişkili, daha önce radyoterapi uygulanmamış maksillofasiyal bölge alveoler kemiklerinin nekrozudur (1,2,3). Hiperbarik oksijen (HBO) kök hücre mobilizasyonu arttırma, ödem, inflamasyonu azaltma ve hasar iyileşmesini hızlandıraması yoluyla, BBCO tedavisinde kullanılan seçeneklerden biridir (4,5). Bu raporda metastatik meme kanserli bir BBCO olgusu sunulacak ve BBCO tedavisinde HBO tartışılacaktır.Keywords : ANAHTAR KELİMELER: Bifosfonata bağlı çene osteonekrozisi (BBCO), Hiperbarik oksijen (HBO), radyoterapi