- Turkish Journal of Medical Sciences
- Vol: 39 Issue: 3
- A rare cause of neonatal hypocalcemia: malignant infantile osteopetrosis
A rare cause of neonatal hypocalcemia: malignant infantile osteopetrosis
Authors : Hakan Uzun, Ebru Yilmaz Keskin, Dursun Şenses, Ayhan Erdem, Bunyamin Dikici, Kenan Kocabay
Pages : 457-460
View : 13 | Download : 8
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Malignant infantile osteopetrosis (MIOP) is a rare inherited bone disease characterized by reduced or dysregulated activity of osteoclasts, which results in generalized osteosclerosis. This leads to abnormal bone marrow cavity formation and to the clinical signs and symptoms of bone marrow failure and nerve compression. Symptoms related to early or late hypocalcemia may appear as the first presentation of MIOP in a newborn. We present a 14-day-old boy with neonatal hypocalcaemia due to MIOP.Keywords : Malignant infantile osteopetrosis, neonatal hypocalcaemia