- Turkish Journal of Internal Medicine
- Vol: 4 - Supplement 1 Special Issue
- Pembrolizumab Induced Hypothyroidism: A Case Report
Pembrolizumab Induced Hypothyroidism: A Case Report
Authors : Sidelya Ecem Yiğit, Iffet Beril Gökmen, Yıldız Okuturlar
Pages : 149-151
Doi:10.46310/tjim.1078792
View : 25 | Download : 22
Publication Date : 2022-04-01
Article Type : Other
Abstract :Immune checkpoint inhibitors inhibit the inhibitory mechanism on the immune system, their side effects may be autoimmune diseases that occur due to excessive immune response. Pembrolizumab is an immune checkpoint inhibitor targeting PD-1. The most common clinical presentations of thyroid injury induced by pembrolizumab are destructive thyroiditis and overt hypothyroidism. Herein, we presented a case of pembrolizumab induced hypothyroidism.Keywords : Pembrolizumab, immune checkpoint inhibitors, lung cancer, hypothyroidism, PD-1, non-small cell lung